shRNA Adeno-associated Virus Serotype 2, pU6-(OR5B3-shRNA-Seq5)(CAT#: AAV-SI2122WQ)
This product is a OR5B3-shRNA encoding AAV, which is based on AAV-2 serotype. The OR5B3 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR5B3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | OR5B3-shRNA-Seq5 |
Related Target/Protein | OR5B3 |
Region | CDS |
TargetSeq | CCTGGGAATTATTGTATTGAT |
NCBI RefSeq | NM_001005469 |
Alternative Names | OR5B13; OST129; OR11-239 |
Titer | >1*10^10 GC/mL |
Related Diseases | Olfactory dysfunction |