shRNA Adeno-associated Virus Serotype 2, pU6-(TMEM156-shRNA-Seq1)(CAT#: AAV-SI0159WQ)
This product is a TMEM156-shRNA encoding AAV, which is based on AAV-2 serotype. TMEM156 is expressed in several tissues including ascites, bone marrow, salivary glands, and vascular to name a few. It should be noted this gene is not ubiquitously expressed, but is still evident in many tissues. This gene is predominately expressed in adults but there is a bit of expression in fetuses. The expression of TMEM156-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV-2 |
Backbone | AAV-2 |
Tropism | CNS, muscle, liver, brain, eye |
Insert | TMEM156-shRNA-Seq1 |
Related Target/Protein | TMEM156 |
Region | CDS |
TargetSeq | GAAGTGTGTTTGCAATCTAAT |
NCBI RefSeq | NM_024943 |
Titer | >1*10^10 GC/mL |
Related Diseases | Breast cancer, liver cancer and prostate cancer |