With unrivaled expertise in various immunotherapy discoveries and development, Creative Biolabs has lots of experience in engineering ovarian cancer cell line A2780 for self-destruction purposes for global clients to speed up the project's development.

Background of Ovarian Cancer

Ovarian cancer is known as one of the most common and deadly gynecological malignancies around the world. The high lethality rate of ovarian cancer is due to a variety of reasons, mainly consisting of relapse and the resistance of recurrent tumors to conventional therapy.

Tumor microenvironment (TME) is regarded as a hot therapeutic target for ovarian cancer. Currently, multiple strategies are adopted to target ovarian TME. Among them, several strategies are currently in clinical use, such as CAFs targeting therapy, and VEGF-R inhibitors therapy, while others are at different phases of clinical development.

Fig.1 Tumor microenvironment-related therapeutic strategies in ovarian cancer. (Yang, et al., 2020)

Engineering Ovarian Cancer Cell A2780 for Self-destruction

Ovarian cancer cell lines are very important for preclinical research, to study the mechanisms of disease, and screening drug candidates for therapy. Human ovarian cancer cell line A2780 was derived from tumor tissue from an untreated patient of ovarian adenocarcinoma. Which is a crucial research tool for ovarian cancer research, featuring a well-characterized ovarian cancer cell line.

Creative Biolabs specializes in engineering ovarian cancer cell line A2780 for self-destruction purposes to speed up clients' project development. Which uses different means to transfect cytokines into ovarian cancer cell line A2780, and activates the immune system to destroy cancer cells.

We are dedicated to providing more comprehensive and targeted accurate analysis results and facilitating scientific research for global customers to meet your research needs. And our scientists and technicians are experienced in every step with high dedication to ensuring accurate outcomes. Our services are characterized by:

• Flexible development assay formats to meet diverse project needs.
• An excellent expert team for providing real-time technical guidance.
• Advanced and optimized assay platform to facilitate the data output.
• Customize experiment types according to customer needs to facilitate project progress.

In addition, we offer the following ovarian cancer research topic including but not limited to:

• Engineering Ovarian Cancer Cell OVCAR-3 for Self-destruction
• Engineering Ovarian Cancer Cell CAOV3 for Self-destruction
• Engineering Ovarian Cancer Cell SK-OV-3 for Self-destruction
• Engineering Ovarian Cancer Cell IGROV1 for Self-destruction

For more details on engineering ovarian cancer cell line A2780 for self-destruction topic, please visit our web for more information. To request other related services, please feel free to contact us to discuss your project.

References

1. Luo, X.; et al. Shaping immune responses in the tumor microenvironment of ovarian cancer. Frontiers in Immunology. 2021, 12:2383.
2. Yang, Y.; et al. Tumor microenvironment in ovarian cancer: function and therapeutic strategy. Frontiers in cell and developmental biology. 2020, 8:758.

For Research Use Only | Not For Clinical Use