HPLC-MS/MS-based Cytochrome P450 2C19 (CYP2C19) Inhibition Assessment Service
Creative Biolabs' HPLC-MS/MS-based CYP2C19 Inhibition Assessment Service provides accurate and reliable data on the inhibition of the CYP2C19 enzyme, which is essential for understanding drug metabolism and potential drug-drug interactions. Our experienced team utilizes state-of-the-art technology to deliver precise results, helping our clients make informed decisions in drug development and personalized medicine. Trust us for high-quality CYP2C19 inhibition assessment services that meet your research and regulatory needs.
HPLC-MS/MS-based CYP Inhibition Assessment Platform
HPLC-MS/MS-based Cytochrome P450 2C19 (CYP2C19) Inhibition Assessment Service
CYP2C19
CYP2C19 is a gene that codes for an enzyme involved in metabolizing drugs in the body. This enzyme is responsible for breaking down a variety of medications, including some commonly prescribed drugs like proton pump inhibitors, antidepressants, and antiplatelet medications. Variations in the CYP2C19 gene can affect how quickly or slowly an individual metabolizes these drugs, leading to differences in drug effectiveness and potential side effects.
What We Do
Our HPLC-MS/MS-based CYP2C19 inhibition assessment service offers a reliable and accurate assessment of the inhibitory effects of test compounds on CYP2C19 enzyme activity. CYP2C19 is a critical enzyme involved in the metabolism of a wide range of drugs, and inhibition of this enzyme can lead to potential drug-drug interactions and toxicity issues.
Our service utilizes HPLC-MS/MS to quantitatively measure the metabolic activity of CYP2C19 in the presence of test compounds. With our expertise in drug metabolism and pharmacokinetics, we can help you assess the inhibitory effects of your compounds on CYP2C19 and provide you with comprehensive data and analysis to support your drug development efforts.
Detailed Information of Our Service
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Protein Name
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Family
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Sub Family
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Uniprot Number
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Gene Name
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|
CYP2C19
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CYP450
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CYP2
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P33261
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CYP2C19
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|
Gene ID
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Gene Aliases
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Organism
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Construct Details
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Tissue
|
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1557
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P450IIC19|CPCJ
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Human
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Microsomes
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Liver
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Measured Response
Peak Area Response
Service Sub Type
Enzymatic
Detection Method
HPLC-MS/MS
Importance of CYP2C19 Inhibition Assessment
CYP2C19 is a key enzyme responsible for metabolizing a significant number of drugs. Inhibition of CYP2C19 can lead to altered drug levels in the body, potentially resulting in treatment failure or adverse effects.
Individuals who are poor metabolizers of CYP2C19 may be at increased risk of drug-drug interactions when taking medications that are substrates for this enzyme. Understanding the inhibition status of CYP2C19 can help healthcare providers tailor drug regimens to minimize the risk of adverse reactions.
Pharmacogenomic testing for CYP2C19 polymorphisms can provide valuable information about an individual's drug metabolism capabilities.
Cooperation With Creative Biolabs
Frequently Asked Question
A1: What is the timeline for the HPLC-MS/MS-based CYP2C19 inhibition evaluation service?
Q1: The timeline for the HPLC-MS/MS-based CYP2C19 inhibition evaluation service may vary depending on the specific requirements and samples involved. The entire process may take approximately 15-20 days from sample receipt to report delivery. However, this timeline can be adjusted based on the number of samples, the complexity of the analysis, and the specific requirements of the project. It is recommended to discuss the timeline with our technicians to ensure timely delivery of results.
Contact Us
For more information or to inquire about our HPLC-MS/MS-based CYP2C19 Inhibition Assessment Service, please contact us right now. Our team of experts is ready to assist you with any questions you may have or to provide you with a quote for our services. We look forward to hearing from you and helping you with your CYP2C19 inhibition assessment needs. Except for Inhibition Assessment Service, We also provide In Vivo Drug Metabolism and Pharmacokinetics (DMPK) Services and In Vitro ADME Services!
For Research Use Only | Not For Clinical Use
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