Despite significant advancements in cancer treatment, we still face challenges with resistance to standard therapies. Welcome to our anti-cancer resistance solutions! Creative Biolabs is excited to offer comprehensive services to help our customers combat cancer resistance. Our services leverage the latest technology and research in the field to provide personalized and targeted treatment options.
Introduction
There are existing solutions and technologies that are being developed to combat cancer resistance, providing hope for improving existing therapy strategies. At Creative Biolabs, innovative technologies are being developed to overcome cancer resistance. Our staff is working on exploring our comprehensive approach to anti-cancer resistance solutions, reducing the risk of resistance, and minimizing side effects.
Fig.1 DNA Damage Repair-caused Radioresistance in Breast Cancer.1,3
Services
The fight against cancer is ongoing, and Creative Biolabs is constantly looking for new ways to combat this devastating disease. Currently, various services can be provided to us to help in the development and implementation of effective cancer-resistance solutions.
Cancer Immunocombination Therapy Development
We use specific antibodies or immune cells to target cancer cells. By utilizing different types of immunotherapies, such as checkpoint inhibitors or CAR-T cell therapy, we can create custom project plans for each client based on the cancer type they are interested in and their genetic makeup.
In Vivo Modeling Services of Anti-Cancer Resistance
Drug resistance is a major challenge in cancer treatment because cancer cells can develop mechanisms to evade the effects of chemotherapy or targeted therapies. We can test potential treatment options in a more realistic environment. By using animal models that closely mimic human tumors, we can better predict how a new drug or treatment will perform in future clinical trials.
Targeted Inhibition of Drug Resistance-related Protein Services
Our targeted inhibition services focus on identifying and targeting the proteins that are responsible for drug resistance, allowing for more effective treatment options. By specifically targeting these proteins, we can help to overcome drug resistance and improve therapy outcomes.
Cancer Resistant Drug Delivery Platform
The delivery of drugs to cancer cells is crucial for effective treatment, and our platform is designed to deliver anticancer drugs directly to the tumor site. Our drug delivery platform is customizable to suit the specific needs of each client, ensuring that they receive the most meaningful data possible.
Immune Checkpoint Blocking (ICB) Therapy Development
We also offer services for the development of ICB therapy. Our ICB therapy solutions lie in its ability to specifically target and block molecules such as PD-1, PD-L1, and CTLA-4, which are known to suppress the immune response. By doing so, the therapy helps to activate the immune system to recognize and attack cancer cells, leading to improved therapy outcomes.
Anti-Cancer Resistance Inhibitor Discovery Solutions
Cancer cells often develop resistance to traditional cancer treatments, making them challenging to eradicate. Anticancer resistance inhibitors work by targeting the mechanisms that cancer cells use to resist treatment, ultimately making them more susceptible to therapy. Furthermore, our solution leverages the latest advancements in bioinformatics and computational modeling to predict the interactions between inhibitors and cancer cells, helping us to optimize their targeting and efficacy.
Highlights
In addition, Creative Biolabs also utilizes advanced imaging techniques to monitor treatment response and identify potential areas of resistance.
For example, we are working on developing nanoparticles that can deliver chemotherapy drugs directly to cancer cells, reducing the risk of resistance and minimizing side effects for patients. Also, we can perform genome-wide RNA sequencing and drug screening to identify key genes and pathways involved in cancer resistance. Up to now, we have identified several key pathways and genes implicated in cancer resistance, including the PI3K/Akt/mTOR pathway, the MAPK pathway, and the ABC transporters. We also found that combination therapies targeting multiple pathways or using novel drug delivery systems could overcome cancer resistance and enhance the efficacy of cancer treatments. Additionally, we found that immunotherapy and targeted therapies directed at specific molecular targets could also help overcome cancer resistance in certain cases.
Fig.2 DOX-PLGA/CPT/PD Mechanisms For Solving Cancer Drug Resistance.2,4
Creative Biolabs would like to extend a warm welcome to customers who are interested in learning more about our anti-cancer resistance solutions. Our team of researchers and experts have developed innovative strategies to combat drug resistance in cancer treatments. By focusing on the underlying mechanisms that drive resistance, we can provide personalized and targeted solutions that can improve the effectiveness of cancer therapies. Whether you are looking to inquire about our services or place an order, we are here to assist you every step of the way. Don't hesitate to contact us and learn more about how we can work together to make a difference in the fight against cancer.
References
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Zhao, Xiaohui, et al. "Mechanisms of traditional Chinese medicine overcoming of radiotherapy resistance in breast cancer." Frontiers in Oncology 14 (2024).
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Hu, Tingting, et al. "Nanomedicines for overcoming cancer drug resistance." Pharmaceutics 14.8 (2022): 1606.
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Image retrieved from Figure 1 "Mechanisms of Radioresistance Caused by DNA Damage Repair in Breast Cancer." Zhao et al., 2024, used under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). The title was changed to " DNA Damage Repair-caused Radioresistance in Breast Cancer."
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Image retrieved from Figure 2 "DOX-PLGA/CPT/PD for overcoming cancer drug resistance." Hu et al., 2022, used under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). The title was changed to " DOX-PLGA/CPT/PD Mechanisms For Solving Cancer Drug Resistance."
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