ACLY Monoclonal Antibody (SJ2-4) (NHP-AB166)

• This product is an antibody that was generated by immunizing mouse against recombinant protein of human ACLY. It is used only in in vitro assays.

Detailed Product Description

• Introduction: ACLY is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: Flow Cytometry; ICC; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Human; Monkey; Mouse
• Immunogen: Recombinant protein of human ACLY

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20⁰C. Avoid freeze-thaw cycles.

Target Information

• Target: ACLY
• Clone: SJ2-4
• Clonality: Monoclonal
• Alternative Names: ACL; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; Citrate cleavage enzyme
• Entrez Gene ID: 47