NHP Based Gene Therapy Platform

Creative Biolabs: Expert in NHP gene therapy solutions!

As a cutting-edge medical technique, gene therapy has shown great potential in improving healthcare outcomes and promoting the life quality of patients. Taking advantage of our non-human primate (NHP) resources within reach, Creative Biolabs has established an easy-to-access gene therapy development platform and is devoted to providing a competitive gene therapy solution based on NHPs for our global customers.

Applications of NHPs in Gene Therapy

Fig.1 Brown monkey on brown wooden surface during daytime (https://unsplash.com/photos/brown-monkey-on-brown-wooden-surface-during-daytime-gYSHsshVZLM)

There is no denying that gene therapy is a very promising and attractive approach for many refractory diseases. However, some technique challenges still exist. For instance, how to avoid immune responses against vectors or transgenes, and how to select the best Adeno-associated virus (AAV) serotype for each disease. Due to their anatomical and physiological similarities to humans, primates possess natural advantages over other large animals in handling these problems as a suitable research model. These primates can help us understand how genes work and how certain gene changes will influence our health, which will enhance the convergence between preclinical efficiency and safety testing and clinical trials.

Our NHP Gene Therapy Platform

At Creative Biolabs, our NHP-based gene therapy platform integrates various advanced facilities. Particularly, our multidisciplinary experts can offer a whole suite of NHP-based preclinical gene therapy development research, such as pharmacology and pharmacodynamics, pharmacokinetics, safety assessment, and biomarker discovery/validation. We have extensive practical experience in multiple therapeutic areas, especially ophthalmology and neurology. Our large stock of multiple monkey species allows you to freely choose the most suitable species for your program. Moreover, in response to urgent needs, we have pre-screened primates negative for AAV to avoid the delay resulting from high seropositive rates or unexpected seroconversion.

Why Choose Us

Creative Biolabs has specialized in NHP research for many years and stays ahead in the breadth and depth of customer services. We always strive for excellence and keep ongoing progress, which has gained a high degree of trust from customers. We are confident that our NHP-based gene therapy platform will benefit your project from the following advantages. For more details, please feel free to contact us.

Fig.2 The strengths of Creative Biolabs in the NHP-based gene therapy platform (Creative Biolabs Original)

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