CD107a Monoclonal Antibody (B4A3), Biotin (NHP-AB090)


  • This product is an antibody conjugated with biotin that was generated by immunizing mice against a human adherent peripheral blood cells. It is used only in in vitro assays.

Detailed Product Description

  • Introduction: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily
    glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins
    on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in
    extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains,
    and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T
    cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some
    tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular
    antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane
    by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and
    CD107b on the surface of tumor cell lines has been associated with their enhanced
    metastatic potential where they may increase adhesion to extracellular matrix and
    endothelium.
  • Conjugate: Biotin
  • Antibody Isotype: IgG1
  • Applications: Flow Cytometry; IHC-Fr; WB; IP

Technical Specifications

  • Host Species: Mouse
  • Species Reactivity: African green Monkey; Human
  • Immunogen: Human adherent peripheral blood cells

Product Property

  • Format: Liquid
  • Buffer: Supplied in PBS/NaN3
  • Storage: Store at 4⁰C.

Target Information

  • Target: CD107a
  • Clone: B4C3
  • Clonality: Monoclonal
  • Alternative Names: CD107 antigen-like family member A; CD107a; LAMP-1; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; lysosome-associated membrane protein 1
  • Entrez Gene ID: 3916
Downloadable Resources Customer Reviews
  • CD107a Monoclonal Antibody (B4A3), Biotin (NHP-AB090) Data Sheet: Detailed information.

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NHP Biologicals from Creative Biolabs are for research, diagnostic, or manufacturing purposes only. They may not be intended for or are not approved for any other use.

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