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Cynomolgus Monkey Bone Marrow Mesenchymal Stem Cells (MKMSC) (NHP-PC179)
Category:Non-Human Primate (NHP) Bone Marrow Cell Products
Tag: Cynomolgus Monkey, Bone Marrow Cells
Tag: Cynomolgus Monkey, Bone Marrow Cells
- Cynomolgus monkey is a widely used primate in biochemical procedures. This available product is derived from the tibias of Cynomolgus monkey. Cells are high-quality and have passed tests of bacteria, yeast, fungi, and mycoplasma, and can be used for many test and assay experiments including PCR, Western blotting, immunoprecipitation, or generating cell derivatives for desired research applications.
Detailed Product Description
- Source: Healthy cynomolgus monkey
- Purity: ≥ 85%
- Applications: Suitable for a wide range of safety assessment and functional assays.
- Organ/Tissue: Bone marrow
Technical Specifications
- Cell Type: Mesenchymal stem cells
- Species: Cynomolgus monkey
- Cryopreservation: Cryopreserved with appropriate cryoprotectant.
- Quality Control: Rigorously control cell purity and viability.
- Cell Status: Cryopreserved
Shipping and storage
- Shipping: Cryopreserved cells are shipped with dry ice overnight. Upon receipt, promptly transfer the frozen cells to liquid nitrogen for storage until they are ready for use. It is important to note that cells should never be stored in -20 °C or -80 °C freezer.
- Storage: Liquid Nitrogen (-180 °C)
Downloadable Resources
Published Data
FAQs
Customer Reviews
This paper thus discusses whether it is of any use that, given its imperativeness in their application to, would be warranted for the use of labeled cynomolgus monkey bone marrow-derived mesenchymal stem cells (MSCs) for cell tracking and characterization. It describes the protocol used for the labeling of MSCs with a special dye (Molday ION Rhodamine-B™), which can be used for that purpose, and demonstrates how to do it in practice for later viability, proliferation, and differentiation assays. Further experiment was carried out to compare both processes. It demonstrated that the method of labeling does no harm to MSCs and allows them to preserve basic functions and abilities. As discussed in the paper, the findings highlight such a potential toward making MSC-based therapies more effective by achieving improved tracking and assessment in support of their use in several therapeutic applications.
1Fig. 1. Differentiation capacity of MIRB-labeled cMSCs
1Fig. 2. Multimodality imaging of MIRB-labeled cMSCs.
Reference
- REN ZhenHua., et al. " Labeling of cynomolgus monkey bone marrow-derived mesenchymal stem cells for cell tracking by multimodality imaging." Sci China Life Sci, 2011, 54: 981–987
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Q 1: How are Cynomolgus Monkey Bone Marrow Mesenchymal Stem Cells isolated for research?
A: The cells are usually separated from the bone marrow tissue by first centrifugation with the density gradient, then culturing with specific media that selects them based on their adherence properties.
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Q 2: What are the key applications of Cynomolgus Monkey Bone Marrow Mesenchymal Stem Cells in research?
A: MSCs derived from adipose are pluripotent stem cells that can differentiate into osteoblasts, chondrocytes, and even adipocytes. Therefore, these are broadly used in the field of regenerative medicine, specifically tissue engineering, for research in cell differentiation.
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Q 3: How are Mesenchymal Stem Cells (MSCs) from Cynomolgus Monkey Bone Marrow utilized in regenerative medicine?
A: These MSCs are used in regenerative medicine for their potential to differentiate into a variety of cell types, including osteoblasts, chondrocytes, and adipocytes. Researchers leverage these capabilities to develop treatments for a range of conditions, from bone and cartilage repair to the modulation of immune responses in autoimmune diseases.
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Consistency and High Quality
I have been using the MKMSCs from Creative Biolabs in my laboratory for the last one year, working on research on tissue regeneration. This has greatly facilitated my ability to repeat experiments due to the consistency and the quality high of cells. Furthermore, customer service has been great, well-informed about their products, and they are fast when it comes to delivering orders. -
Thoroughly Impressed
Our project required the most viable mesenchymal stem cells for some complex study of immunomodulation. According to the published characteristics, it was decided to try MKMSCs. The cells have completely met our expectations and, moreover, showed a very high potential for differentiation. I'm thoroughly impressed with the product and the technical support provided.
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NHP Biologicals from Creative Biolabs are for research, diagnostic, or manufacturing purposes only. They may not be intended for or are not approved for any other use.
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