MDA5 Polyclonal Antibody (NHP-AB402)

• This product is an antibody that was generated by immunizing goat against SNGYSTDENFRYL-C. It is used only in in vitro assays.

Detailed Product Description

• Introduction: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
• Conjugate: None
• Applications: ELISA; IHC; WB

Technical Specifications

• Host Species: Goat
• Species Reactivity: Human; Monkey
• Immunogen: SNGYSTDENFRYL-C

Product Property

• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Format: Liquid
• Concentration: 500 ug/mL
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Storage: Store at -20⁰C. Avoid freeze-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; Helicard; Helicase with 2 CARD domains; Interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; Interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; Melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116
• Entrez Gene ID: 64135