p27 Monoclonal Antibody (G2C2) (NHP-AB232)

• This product is an antibody that was generated by immunizing mouse against mouse recombinant protein. It is used only in in vitro assays.

Detailed Product Description

• Introduction: p27 is a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This mAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
• Conjugate: None
• Antibody Isotype: IgG1κ
• Applications: Flow Cytometry; IF; IHC-P; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: Mouse recombinant protein

Product Property

• Purification: Protein G affinity chromatography
• Format: Liquid
• Concentration: 0.2 mg/mL
• Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
• Storage: Store at 4⁰C. Avoid freeze-thaw cycles.

Target Information

• Clone: G2C2
• Clonality: Monoclonal
• Alternative Names: p24 family protein gamma-3; p24gamma3; p27; Transmembrane emp24 domain-containing protein 7; transmembrane emp24 protein transport domain containing 7
• Entrez Gene ID: 1027