PHB Polyclonal Antibody (NHP-AB423)

• This product is an antibody that was generated by immunizing rabbit against recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human PHB (NP_002625.1). It is used only in in vitro assays.

Detailed Product Description

• Introduction: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human PHB (NP_002625.1)

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: B-cell receptor-associated protein 32; BAP 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; Prohibitin
• Entrez Gene ID: 5245