- This product is an antibody that was generated by immunizing rabbit against a synthetic peptide of human PKM. It is used only in in vitro assays.
Detailed Product Description
- Introduction: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
- Conjugate: None
- Antibody Isotype: IgG
- Applications: IF; IHC; WB
Technical Specifications
- Host Species: Rabbit
- Species Reactivity: Human; Monkey; Mouse; Rat
- Immunogen: A synthetic peptide of human PKM
Product Property
- Purification: Affinity purification
- Format: Liquid
- Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Storage: Store at 4⁰C. Avoid freez-thaw cycles.
Target Information
- Clonality: Polyclonal
- Alternative Names: CTHBP; Cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; isozymes M1/M2; m2pk; OIP-3; OPA-interacting protein 3; p58; PK, muscle type; Pyruvate kinase 2/3; pyruvate kinase 3; pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase PKM; THBP1; Thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tu; Tumor M2-PK
- Entrez Gene ID: 5315
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