PRMT5 Polyclonal Antibody (NHP-AB430)

• This product is an antibody that was generated by immunizing rabbit against a synthetic peptide corresponding to a sequence within amino acids 40-140 of human PRMT5 (NP_006100.2). It is used only in in vitro assays.

Detailed Product Description

• Introduction: PRMT5 is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 40-140 of human PRMT5 (NP_006100.2)

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: 72 kDa ICln-binding protein; EC 2.1.1.125; Histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; Jak-binding protein 1; PRMT5; Protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; Shk1 kinase-binding protein 1 homolog; SKB1 homolog
• Entrez Gene ID: 10419