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Biotin-PEG2-Mal (CAT#: ADC-L-Y0328)
Biotin-PEG2-Mal is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
- Product Information
- CAS NO
- 305372-39-8
- Description
- Biotin-PEG2-Mal is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
- Molecular Weight
- 525.6
- Purity
- 95%
- Formula
- C23H35N5O7S
- Group 1
- Biotin
- Functional Group 1
- Biotin
- PEG/Non-PEG
- PEG
- Cleavable/Non-cleavable
- Non-cleavable
- Group 2
- Maleimides
- Reactive Group 2
- Maleimides
- Storage Condition
- -20 ° C
- Shipping
- Ambient Temperature
For Research Use Only. NOT FOR CLINICAL USE.
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