Anti-Drug Antibody Products
Antibody-drug conjugates (ADCs) are new-generation anti-cancer immunotherapeutic agents that accurately deliver cytotoxic agents to cancer cells to achieve caner elimination without damaging normal tissues. ADCs carry extremely high potent toxins and their pharmacokinetic properties and safety profile need to be extensively evaluated before deploying to human clinical trials. One crucial aspect in ADC pharmacokinetic (PK) property is the ratio of total and conjugated antibody after certain time period of deployment. This is usually assayed using immuno-colorimetric assay methods such as ELISA. To detect and quantify conjugated antibody, an agent that targets the drug portion of the ADC is desired.
Due to the high potency of ADC toxins, antibodies against these chemical compounds are difficult to develop. Only low dosages of a toxin can be applied for animal immunization and the corresponding immune response is low in small rodents. After devoting a tremendous amount of effort, Creative Biolabs has raised a series of antibodies, collectively anti-drug Abs, against ADC toxin antigens include MMAE, MMAF, DM1, DM4, Calicheamicin, Duocarmycin…. These anti-drug Abs will be valuable assets to facilitate the PK and safety evaluation of newly developed ADCs bearing these drugs.
List of the anti-drug Ab products
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Mouse Anti-Dxd Monoclonal Antibody (clone 1)(WJY-1122-LS1)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: DNA inhibitor
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- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: DNA inhibitor
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HRP-Mouse Anti-Dxd Monoclonal Antibody (clone 1)(WJY-1122-LS3)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: DNA inhibitor
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Mouse Anti-Dxd Monoclonal Antibody (clone 2)(WJY-1122-LS4)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: DNA inhibitor
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Mouse Anti-MMAE Monoclonal Antibody (clone 1)(WJY-1122-LS5)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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HRP-Mouse Anti-MMAE Monoclonal Antibody (clone 1)(WJY-1122-LS6)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-MMAE Monoclonal Antibody (clone 3)(WJY-1122-LS7)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-MMAF Monoclonal Antibody (clone 1)(WJY-1122-LS8)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-MMAF Monoclonal Antibody (clone 2)(WJY-1122-LS9)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-MMAF Monoclonal Antibody (clone 4)(WJY-1122-LS10)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-Amanitin Monoclonal Antibody (clone a4)(WJY-1122-LS11)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Amanitin. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: RNA polymerase Ⅱ inhibitor
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Mouse Anti-DM1 Monoclonal Antibody (clone 1)(WJY-1122-LS12)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-DM1 Monoclonal Antibody (clone 2)(WJY-1122-LS13)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Mouse Anti-DM1 Monoclonal Antibody (clone 3)(WJY-1122-LS14)
- Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
- Host animal: Mouse
- Payload Category: Tubulin inhibitor
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Goat Anti-Pseudomonas exotoxin A Polyclonal Antibody(WJY-1122-LS15)
- Product overview: This product is a Goat Polyclonal antibody which specifically againsts the Pseudomonas exotoxin A. This product is for research purposes only, not for use in diagnostics.
- Host animal: Goat
- Payload Category: Toxin
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Rabbit Anti-Diphtheria Toxin Polyclonal Antibody(WJY-1122-LS16)
- Product overview: This product is a Rabbit Polyclonal antibody which specifically againsts the Diphtheria Toxin. This product is for research purposes only, not for use in diagnostics.
- Host animal: Rabbit
- Payload Category: Toxin
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Rabbit Anti-Beta glucuronidase Polyclonal Antibody(WJY-1122-LS17)
- Product overview: This product is a Rabbit Polyclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
- Host animal: Rabbit
- Payload Category: Enzyme
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Rabbit Anti-Beta glucuronidase Monoclonal Antibody (clone 1)(WJY-1122-LS18)
- Product overview: This product is a Rabbit Monoclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
- Host animal: Rabbit
- Payload Category: Enzyme
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Sheep Anti-Beta glucuronidase Polyclonal Antibody(WJY-1122-LS19)
- Product overview: This product is a Sheep Polyclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
- Host animal: Sheep
- Payload Category: Enzyme
For Research Use Only. NOT FOR CLINICAL USE.
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