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Anti-Drug Antibody Products

Antibody-drug conjugates (ADCs) are new-generation anti-cancer immunotherapeutic agents that accurately deliver cytotoxic agents to cancer cells to achieve caner elimination without damaging normal tissues. ADCs carry extremely high potent toxins and their pharmacokinetic properties and safety profile need to be extensively evaluated before deploying to human clinical trials. One crucial aspect in ADC pharmacokinetic (PK) property is the ratio of total and conjugated antibody after certain time period of deployment. This is usually assayed using immuno-colorimetric assay methods such as ELISA. To detect and quantify conjugated antibody, an agent that targets the drug portion of the ADC is desired.

Due to the high potency of ADC toxins, antibodies against these chemical compounds are difficult to develop. Only low dosages of a toxin can be applied for animal immunization and the corresponding immune response is low in small rodents. After devoting a tremendous amount of effort, Creative Biolabs has raised a series of antibodies, collectively anti-drug Abs, against ADC toxin antigens include MMAE, MMAF, DM1, DM4, Calicheamicin, Duocarmycin…. These anti-drug Abs will be valuable assets to facilitate the PK and safety evaluation of newly developed ADCs bearing these drugs.

Anti-drug Abs

List of the anti-drug Ab products

    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: DNA inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: DNA inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: DNA inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Dxd. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: DNA inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAE. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the MMAF. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the Amanitin. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: RNA polymerase Ⅱ inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Mouse Monoclonal antibody which specifically againsts the DM1. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Mouse
    • Payload Category: Tubulin inhibitor
    • Product overview: This product is a Goat Polyclonal antibody which specifically againsts the Pseudomonas exotoxin A. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Goat
    • Payload Category: Toxin
    • Product overview: This product is a Rabbit Polyclonal antibody which specifically againsts the Diphtheria Toxin. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Rabbit
    • Payload Category: Toxin
    • Product overview: This product is a Rabbit Polyclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Rabbit
    • Payload Category: Enzyme
    • Product overview: This product is a Rabbit Monoclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Rabbit
    • Payload Category: Enzyme
    • Product overview: This product is a Sheep Polyclonal antibody which specifically againsts the Beta glucuronidase. This product is for research purposes only, not for use in diagnostics.
    • Host animal: Sheep
    • Payload Category: Enzyme
If you can’t find your product on this list? Please directly send email to info@creative-biolabs.com

For Research Use Only. NOT FOR CLINICAL USE.

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