shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(TXNDC5-shRNA-Seq1)(CAT#: AdV-SI3316WQ)
This product is a TXNDC5-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The TXNDC5 gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The expression of TXNDC5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | TXNDC5-shRNA-Seq1 |
Related Target/Protein | TXNDC5 |
Region | CDS |
TargetSeq | CGAAACTGTCAAGATTGGCAA |
NCBI RefSeq | NM_022085 |
Alternative Names | HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI |
Titer | >1*10^10 GC/mL |
Related Diseases | Disulfide-isomerase deficiency |