shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(MTRF1L-shRNA-Seq1)(CAT#: AdV-SI0867WQ)
This product is a MTRF1L-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The protein encoded by MTRF1L gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. The expression of MTRF1L-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | MTRF1L-shRNA-Seq1 |
Related Target/Protein | MTRF1L |
Region | CDS |
TargetSeq | CGGGTCACAGATCACAGAATA |
NCBI RefSeq | NM_019041 |
Alternative Names | MRF1L; HMRF1L; mtRF1a |
Titer | >1*10^10 GC/mL |