shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(PIGX-shRNA-Seq1)(CAT#: AdV-SI2047WQ)
This product is a PIGX-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The PIGX gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER) and the protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I. The expression of PIGX-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | PIGX-shRNA-Seq1 |
Related Target/Protein | PIGX |
Region | CDS |
TargetSeq | GAAGCCTCGATTGTGGTCAAT |
NCBI RefSeq | NM_017861 |
Alternative Names | PIG-X |
Titer | >1*10^10 GC/mL |