shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Tmem146-shRNA-Seq2)(CAT#: AdV-SI1977WQ)
This product is a Tmem146-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Tmem146 gene encodes auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. The expression of Tmem146-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Tmem146-shRNA-Seq2 |
Related Target/Protein | Tmem146 |
Region | CDS |
TargetSeq | CAGACAAACAACAAGATTATT |
NCBI RefSeq | XM_001052081 |
Alternative Names | CATSPERD |
Titer | >1*10^10 GC/mL |
Related Diseases | Infertility |