shRNA Lentivirus (self-inactivating), p7SK-(C3orf37-shRNA-Seq1)(CAT#: LV-SI1407WQ)

This product is a C3orf37-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The C3orf37 gene acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The expression of C3orf37-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert C3orf37-shRNA-Seq1
Related Target/Protein C3orf37
Region CDS
TargetSeq CTACCAACTGTCGTAGTGATA
NCBI RefSeq NM_020187
Alternative Names DC12; SRAPD1; HMCES
Titer >1*10^10 GC/mL
Related Diseases DNA demethylation
Target Gene
Gene ID 56941
Uniprot ID Q96FZ2

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