shRNA Lentivirus (self-inactivating), pU6-(PIGY-shRNA-Seq2)(CAT#: LV-SI0068WQ)

This product is a PIGY-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by PIGY gene, which is well-conserved, is encoded by the same bicistronic transcript that encodes phosphatidylinositol glycan anchor biosynthesis, class Y, but the two proteins are unrelated. The expression of PIGY-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert PIGY-shRNA-Seq2
Related Target/Protein PIGY
Region CDS
TargetSeq GATGACACGTCAAAGTAAGAA
NCBI RefSeq NM_032906
Alternative Names PREY
Titer >1*10^10 GC/mL
Related Diseases Hyperphosphatasia and mental retardation syndrome
Target Gene
Gene ID 100996939
Uniprot ID Q96I23

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