shRNA Lentivirus (self-inactivating), pU6-(Sash3-shRNA-Seq1)(CAT#: LV-SI2246WQ)

This product is a Sash3-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Sash3 gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes. The expression of Sash3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Sash3-shRNA-Seq1
Related Target/Protein Sash3
Region 3UTR
TargetSeq CCACTATCCTTCTCAACATTT
NCBI RefSeq NM_028773
Alternative Names SLY; 753P9; HACS2; CXorf9; SH3D6C
Titer >1*10^10 GC/mL
Related Diseases Lymphoma
Target Gene
Gene ID 54440
Uniprot ID O75995

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