shRNA Adeno-associated Virus Serotype 2, pH1-(Prb1-shRNA-Seq1)(CAT#: AAV-SI3164WQ)

This product is a Prb1-shRNA encoding AAV, which is based on AAV-2 serotype. The Prb1 gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. The expression of Prb1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV-2
Backbone AAV-2
Tropism CNS, muscle, liver, brain, eye
Insert Prb1-shRNA-Seq1
Related Target/Protein Prb1
Region CDS
TargetSeq CGAAGACTCAAATTCTCAGCT
NCBI RefSeq NM_198669
Alternative Names PM; PMF; PMS; PRB1L; PRB1M
Titer >1*10^10 GC/mL
Target Gene
Gene ID 5542
Uniprot ID P04280

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