Immuno-oncology Cell Assay Services
Cell-based assays are valuable tools in drug discovery, in which process, reducing the toxicity in drug development is a big challenge for the pharmaceutical industry. Creative Biolabs has developed a panel of live cell assays to enable the investigation of basic cell biology and drug discovery.
Cell Lines Available
Ex Vivo Cell Subsets Available
Assays offered
Offering a relevant representation of a real-life model, cell-based assays enable the tracking of variables, including the number of cells, the behavior, cell proliferation, apoptosis, signal transduction, enzyme activity, reporter gene activity, Antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC), as well as neutralizing antibody (NAb) assays.
Creative Biolabs has over a decade of proven expertise in the research of cell-based assays. Our service offering comprises full cell-based assay analytical methods. Our full portfolio of cell-based assays comes in a ready format. Please send us your cell line of choice, we will develop assay-ready cells with low variability.
Our Featured Assays
Our Assay Endpoints
Our expert team at Creative Biolabs is able to assist you in performing flow cytometry-based assays to profile cell characteristics in your samples.
Scientists at Creative Biolabs have profound knowledge of cellular models and expertise in fibrosis pathology. We've developed robust in vitro models that are specially designed for the accurate study of organ-specific fibrosis.
Applications of Cell Assay for Drug Discovery
High-throughput screening (HTS) has been widely applied in discovery and drug development, which is a challenging process featured with expensive and time time-consuming, full of failures. Cell-based assays have been integrated with HTS technologies, which are unable to reflect the complexity of living systems. To address this problem, in vitro cell culture models are used to get substantive information on various cellular responses to a compound. Combining advanced microscopy with cell-based assays can monitor both spatial and temporal resolution, which has driven the development of HCS technologies.
Blew is HCS-compatible, biochemical, and molecular biology-driven assays for drug discovery, which are available at Creative Biolabs.
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Immunohistochemistry (IHC)-Based Assays
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Quantification of drug target proteins
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Identification of subcellular localization
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Phenotypic characterization
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Cell-ECM interaction studies
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RNA interference (RNAi) Screening
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Functional genomics
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Validation of new targets
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Therapeutic drug repositioning
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Reporter gene assay (RGA)
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Studies for gene expression and regulation
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Phenotypic characterization
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Mechanism-based toxicity assays
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Cell-cell and cell-ECM interaction studies
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CRISPR-Cas9
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Functional genomics
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Phenotypic characterization
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Quantification of target proteins
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Protein-Protein Interaction
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Identification of protein-protein interactions
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Identification of small-molecule-targeted pathways
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Identification of novel targets
Cell assays can accelerate and enhance the process of drug identification and development to help new therapeutics be brought to market in an efficient manner.
Cell-based assays offer help in the following:
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Lead candidate selection
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To determine the biological activity of drug and drug substance
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To determine the mechanism of action (MOA)
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Drug efficacy
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Safety testing
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Toxicity testing
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Off-target effects in a cellular environment
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Early-stage proof of principal studies
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Immunogenicity studies
Creative Biolabs provides a comprehensive array of validated cell-based assays and full support for drug development. We work with our clients to come up with best assay for the proposal. Please contact us for more detailed information on cell-based assays.
For Research Use Only | Not For Clinical Use
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