LC-MS-based Bioanalysis Service

LC-MS-based Bioanalysis Accelerating Drug Discovery and Development

Liquid chromatography-mass spectrometry (LC-MS) has emerged as a foundational tool in drug discovery, facilitating accurate and sensitive analysis of small molecules, peptides, proteins, and biomarkers. The comprehensive bioanalysis offered by LC-MS techniques is instrumental in understanding key parameters such as pharmacokinetics (PK), toxicokinetics (TK), bioavailability (BA), and exposure-response relationships, which play a key role in accelerating the drug development process and ensuring the safety and efficacy of drug products.

Our LC-MS-Based Bioanalysis Service

Equipped with advanced LC-MS technologies, Creative Biolabs offers tailored solutions for small molecules, peptides, and proteins using liquid chromatography-mass spectrometry (LC/MS). Our team of highly experienced scientists understands the unique requirements of each study and offers customized solutions tailored to clients' specific needs. From method development to sample analysis, our bioanalytical services are designed to support diverse studies, ranging from discovery through pre-clinical trials.

Our Capabilities

Utilizing liquid/liquid, solid-phase extraction (SPE), and protein precipitation techniques in both standard and 96-well formats for comprehensive sample preparation.
Implementing high-throughput automated liquid handling systems to accommodate studies of varying volumes efficiently.
Offering in-depth analysis of peptides, pegylated drugs, and related metabolites to meet diverse research needs.

Application Area of LC-MS-based Bioanalysis Service

At Creative Biolabs, we leverage LC-MS for a diverse range of applications, including the analysis of oncology drugs, DNA adducts, free fatty acids, amino acids, and cardiovascular devices. Our expertise extends to developing and validating LC-MS/MS methods for a wide array of analytes across different matrices, highlighting the adaptability and robustness of our bioanalytical services.

What We Can Offer

Comprehensive Bioanalytical Services: Our bioanalytical laboratories are equipped with state-of-the-art technology to offer a range of services.
Expertise in Method Development and Validation: With experienced staff well-versed in the development and validation of small and mid-size peptides, fusion proteins, monoclonal antibodies, and biotherapeutics, we ensure high-quality and accurate results.
Effective Sample Processing and Analysis: We specialize in 96-well sample processing and analysis, and our bioanalytical methods cover a diverse range of compounds, including cardiovascular devices, free fatty acids, amino acids, and more.
Regulatory Compliance and GLP Standards: Our commitment to adhering to Good Laboratory Practices (GLP) ensures that all our bioanalytical methods meet the regulatory standards set by FDA, OECD, and MHLW.
Rapid Turnaround Time and Sponsor Engagement: We collaborate closely with sponsors to ensure open lines of communication, transparency, and efficiency in our services.

With a focus on precision, efficiency, and regulatory compliance, our bioanalytical solutions are tailored to meet the diverse needs of pharmaceutical research. If you have any questions about the LC-MS-based bioanalysis services, please feel free to communicate with us.

For Research Use Only | Not For Clinical Use