Metabolite Profiling Service
Introduction of Metabolite Profiling
Metabolite profiling plays a pivotal role in the field of drug development by providing valuable insights into the fate of investigational products (IPs) in humans. Understanding the routes of elimination, identifying metabolites and their intermediates, and predicting potential drug-drug interactions are essential aspects of metabolite profiling. As a leading provider of biological services, Creative Biolabs offers comprehensive metabolite profiling services to support drug discovery and safety studies.
Metabolite Profiling Services at Creative Biolabs
By conducting comprehensive metabolite profiling studies, researchers can gain vital information on the pharmacokinetics and pharmacodynamics of a compound, assess the potential risks associated with toxic metabolites, and optimize drug dosing regimens. Metabolite profiling also enables the identification of active metabolites that may have superior properties compared to the parent compound, leading to the development of more effective and safer drugs. At Creative Biolabs, we are committed to providing a wide range of metabolite profiling services tailored to meet the diverse needs of the pharmaceutical, agrochemical, and veterinary industries. Our team of experienced scientists specializes in the design and implementation of bespoke metabolite profiling experiments to overcome complex analytical challenges.
Our metabolite profiling service encompasses metabolites in biological matrices of sampling, extraction, analysis, and identification, in order to support drug discovery and safety studies. We utilize state-of-the-art technologies, such as the high-resolution LC-MS/MS, the latest analysis software to achieve precise and detailed metabolite structural data and quantification of low-concentration analytes.
Fig.1 Workflow for metabolic profiling.
Our Capabilities
At Creative Biolabs, we pride ourselves on our commitment to excellence and innovation in metabolite profiling. Our capabilities include:
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Specialized Sample Processing
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Targeted Metabolomic Profiling
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Custom Panels
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Comprehensive Reporting
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We adopt advanced techniques for sample preparation and analysis to deliver reliable and accurate results.
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Through LC-MS and GC-MS, we offer targeted metabolomic profiling services, focusing on specific metabolite classes or pathways.
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Our team can design custom metabolomic panels to address unique research questions or project requirements.
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We deliver detailed metabolomic reports and interpretations, providing clients with actionable insights for their drug development programs.
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We are equipped with cutting-edge technologies and software packages to facilitate the accurate identification and structural elucidation of metabolites. The use of mass spectrometry and nuclear magnetic resonance spectroscopy allows us to optimize sensitivity, resolution, and absolute structure determination, ensuring that we deliver high-quality metabolite profiling services to our clients.
Frequently Asked Questions
Q1: What is the difference between metabolite profiling and metabolomics profiling?
A1: Metabolite profiling includes the search for compound-related metabolites in complex biological samples, as well as a series of metabolite quantification, characterization, and evaluation of (biological) transformation pathways. While metabolomics profiling measures the effect of a test compound of interest on the broader biological system and the full set of metabolites in cells, tissues and organs.
For more details about our comprehensive metabolite profiling solutions, please feel free to get in touch with us.
For Research Use Only | Not For Clinical Use
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