Bloom Syndrome (phospho Ser186) Polyclonal Antibody (NHP-AB493)

• This product is an antibody that was generated by immunizing rabbit against a synthetic peptide surrounding amino acid S186. It is used only in in vitro assays.

Detailed Product Description

• Introduction: The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: ELISA; IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Mouse; Monkey; Rat
• Immunogen: A synthetic peptide surrounding amino acid S186

Product Property

• Purification: Affinity purification
• Format: Liquid

Target Information

• Clonality: Polyclonal
• Alternative Names: Bloom syndrome protein; Bloom syndrome, RecQ helicase-like; DNA helicase, RecQ-like type 2; MGC126616; MGC131618; MGC131620; RecQ protein-like 3; RecQ2
• Entrez Gene ID: 641