c-Jun Monoclonal Antibody (WA-19) (NHP-AB177)

• This product is an antibody that was generated by immunizing rabbit against recombinant protein of human c-Jun. It is used only in in vitro assays.

Detailed Product Description

• Introduction: c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: ChIP; IF; IHC; IP; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: Recombinant protein of human c-Jun

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20˚C. Avoid freeze / thaw cycles.

Target Information

• Target: c-Jun
• Clone: WA-19
• Clonality: Monoclonal
• Alternative Names: Activator protein 1; AH119; AP1; cjun; enhancer-binding protein AP1; immediate early; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; JUND; p39; Proto-oncogene c-Jun; Transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
• Entrez Gene ID: 3725