MAPK13 Polyclonal Antibody (NHP-AB399)

• This product is an antibody that was generated by immunizing rabbit against a KLH conjugated synthetic peptide between 335-365 amino acids from the C-terminal region of human MAPK13. It is used only in in vitro assays.

Detailed Product Description

• Introduction: MAPK13 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
• Conjugate: None
• Applications: IHC-P; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: A KLH conjugated synthetic peptide between 335-365 amino acids from the C-terminal region of human MAPK13

Product Property

• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Format: Liquid
• Buffer: PBS with 0.09% (W/V) sodium azide.
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: MAP kinase 13; MAP kinase p38 delta; MAPK 13; mitogen activated protein kinase 13; Mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta MAP kinase; SAPK/Erk/kinase 4; Stress-activated protein kinase 4
• Entrez Gene ID: 5603