Cynomolgus Monkey PBMCs- Rhesus Monkey PBMCs
- Cynomolgus Monkey Cerebrospinal Fluid (CSF)
- Non-Human Primate (NHP) Plasma Products
- Non-Human Primate (NHP) Serum Products
- NHP Hepatocyte, Stellate Cell, Kupffer Cell Products
- Immortalized Epithelial Cells
- Immortalized NHP Endothelial Cells
- Immortalized NHP Fibroblasts
- Immortalized Smooth Muscle Cells
- Immortalized GFP-Expressing Cells
- GFP Expressing Cells
- RFP Expressing Cells
- Luciferase Expressing Cells
- Cre Expressing Cells
- Cas9 Expressing Cells
- This product is an antibody that was generated by immunizing rabbit against human leukocytes. It is used only in in vitro assays.
Detailed Product Description
- Introduction: C5aR1, also known as CD88, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5aR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. C5aR1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, C5aR1 stimulates chemotaxis, granule enzyme release and superoxide anion production. C5aR1 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with C5aR1 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
- Conjugate: None
- Applications: IHC
Technical Specifications
- Host Species: Rabbit
- Species Reactivity: Chimpanzee; Gorilla; Human; Monkey; Orangutan
- Immunogen: A KLH conjugated synthetic peptide of Synthetic peptide - KLH conjugatedC5AR1
Product Property
- Purification: Immunoaffinity Chromatography
- Format: Liquid
- Concentration: 1 mg/mL
- Buffer: PBS, 0.1% sodium azide
- Storage: Short term: 4˚C. Long term: Store at -20˚C.
Target Information
- Clonality: Polyclonal
- Alternative Names: C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5a-R; CD88; CD88 antigen; complement component 5, receptor 1
- Entrez Gene ID: 728
Downloadable Resources
FAQs
Customer Reviews
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Q 1: How specific is the C5AR1 Polyclonal Antibody for detecting C5AR1 in different species?
A: The specificity of the C5AR1 Polyclonal Antibody for detecting C5AR1 across various species depends on the antibody's epitope recognition. It's essential to verify if the antibody has been validated for cross-reactivity in species of interest. Confirm this data with the supplier's validation studies or inquire directly with customer support.
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Q 2: What are the storage conditions recommended for the C5AR1 Polyclonal Antibody?
A: The C5AR1 Polyclonal Antibody should ideally be stored at -20°C or -80°C. For short-term storage (up to one month), it can be kept at 4°C. Avoid repeated freeze-thaw cycles, as they can impact the integrity of the antibody.
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Q 3: Can the C5AR1 Polyclonal Antibody be used for flow cytometry applications?
A: The usability of the C5AR1 Polyclonal Antibody in flow cytometry depends on its validation and the presence of specific protocols. Check the product datasheet or contact technical support for details regarding flow cytometry compatibility. If not validated, empirical testing might be required.
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High Specificity
I've been using the C5AR1 Polyclonal Antibody from Creative Biolabs in my immunohistochemistry experiments, and the results have been outstanding. The antibody offers high specificity and clean staining patterns, which have significantly contributed to the reliability of my data. -
Robust Performance
The C5AR1 Polyclonal Antibody provided by Creative Biolabs exceeded my expectations. The batch consistency and robust performance in Western Blot experiments have made it a staple in my lab. I highly recommend it to colleagues looking for reliable detection of C5AR1.
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NHP Biologicals from Creative Biolabs are for research, diagnostic, or manufacturing purposes only. They may not be intended for or are not approved for any other use.
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