Heme Oxygenase 1 (HMOX1) Polyclonal Antibody (NHP-AB374)

• This product is an antibody that was generated by immunizing rabbit against synthetic peptide derived from sequence near the amino-terminus of human HO-1 (Hsp32). It is used only in in vitro assays.

Detailed Product Description

• Introduction: Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
• Conjugate: None
• Applications: WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rabbit; Rat
• Immunogen: Synthetic peptide derived from sequence near the amino-terminus of human HO-1 (Hsp32)

Product Property

• Purification: Protein A Column
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.09% azide, 50% glycerol
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: Heat shock protein, 32-kD; heme orygenase 1; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; Heme oxygenase 1; hemoxygenase; HO-1; HSP32; P32 protein
• Entrez Gene ID: 3162