PDGFRA Polyclonal Antibody (NHP-AB419)

• This product is an antibody that was generated by immunizing rabbit against synthetic peptide corresponding to amino acids 1035-1053 of human PDGF (KLH-conjugated). It is used only in in vitro assays.

Detailed Product Description

• Introduction: PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IHC; IP; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Dog; Gorilla; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat; Xenopus
• Immunogen: Synthetic peptide corresponding to amino acids 1035-1053 of human PDGF (KLH-conjugated)

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Buffer: 0.2 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF-R-alpha; pdgfr-a; PDGFR-alpha; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor alpha
• Entrez Gene ID: 5156