SLC12A2 Polyclonal Antibody (NHP-AB455)

• This product is an antibody that was generated by immunizing rabbit against synthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1. It is used only in in vitro assays.

Detailed Product Description

• Introduction: SLC12A2 mediates sodium and chloride transport and reabsorption. SLC12A2 is a membrane protein and is important in maintaining proper ionic balance and cell volume. SLC12A2 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, SLC12A2 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for SLC12A2.
• Conjugate: None
• Applications: IHC

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bat; Bovine; Dog; Gibbon; Hamster; Horse; Human; Monkey; Mouse; Pig; Rat
• Immunogen: Synthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.1% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Related Disease: Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
• Alternative Names: Basolateral Na-K-Cl symporter; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; protein phosphatase 1, regulatory subunit 141; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; Solute carrier family 12 member 2; solute carrier family 12, member 2
• Entrez Gene ID: 6558