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ADC Linker Products

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Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

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Catalog Product name CAS NO Structure Molecular Weight Purity Data sheet Inquiry
ADC-L-Y0277 Benzyl-PEG5-amine 86770-77-6 Benzyl-PEG5-amine 327.4 95% Inquiry
ADC-L-Y0279 Benzyl-PEG5-azide 86770-72-1 Benzyl-PEG5-azide 353.4 95% Inquiry
ADC-L-Y0285 Benzyl-PEG3-CH2CO2tBu 1643957-26-9 Benzyl-PEG3-CH2CO2tBu 310.4 95% Inquiry
ADC-L-Y0286 Benzyl-PEG4-CH2CO2tBu 1443467-88-6 Benzyl-PEG4-CH2CO2tBu 354.4 95% Inquiry
ADC-L-Y0287 Benzyl-PEG5-CH2CO2tBu 1807503-89-4 Benzyl-PEG5-CH2CO2tBu 398.5 95% Inquiry
ADC-L-Y0288 Benzyl-PEG6-CH2CO2tBu 1807537-31-0 Benzyl-PEG6-CH2CO2tBu 442.6 95% Inquiry
ADC-L-Y0290 Benzyl-PEG6-Ms 1807539-07-6 Benzyl-PEG6-Ms 406.5 95% Inquiry
ADC-L-Y0291 Benzyl-PEG2-Tos 4981-83-3 Benzyl-PEG2-Tos 306.4 95% Inquiry
ADC-L-Y0292 Benzyl-PEG3-Tos 98627-22-6 Benzyl-PEG3-Tos 350.4 95% Inquiry
ADC-L-Y0294 Biotin-PEG3-acid 252881-76-8 Biotin-PEG3-acid 447.6 95% Inquiry
ADC-L-Y0295 Biotin-PEG4-acid 721431-18-1 Biotin-PEG4-acid 491.6 95% Inquiry
ADC-L-Y0296 Biotin-PEG6-acid 1352814-10-8 Biotin-PEG6-acid 579.7 95% Inquiry
ADC-L-Y0297 Biotin-PEG8-acid 2143964-62-7 Biotin-PEG8-acid 667.8 95% Inquiry
ADC-L-Y0298 Biotin-PEG12-acid 1621423-14-0 Biotin-PEG12-acid 844 95% Inquiry
ADC-L-Y0299 Biotin-PEG24-acid 721431-18-1 Biotin-PEG24-acid 1372.7 95% Inquiry
ADC-L-Y0300 Biotin-PEG36-acid 948595-11-7 Biotin-PEG36-acid 1901.3 95% Inquiry
ADC-L-Y0303 Biotin-PEG3-NHS ester 1253286-56-4 Biotin-PEG3-NHS ester 544.6 95% Inquiry
ADC-L-Y0304 Biotin-PEG4-NHS ester 459426-22-3 Biotin-PEG4-NHS ester 588.7 95% Inquiry
ADC-L-Y0305 Biotin-PEG6-NHS ester 2055045-04-8 Biotin-PEG6-NHS ester 676.8 95% Inquiry
ADC-L-Y0306 Biotin-PEG8-NHS ester Biotin-PEG8-NHS ester 764.9 95% Inquiry
If you can’t find your product on this list? Please directly send email to info@creative-biolabs.com

For Research Use Only. NOT FOR CLINICAL USE.

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