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ADC Linker Products

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Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform
Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3
Development of Monoclonal Antibodies
Creative Biolabs ADC Product Brochure
CAMouse™-Fully Human Antibody Generation Platform
Protocol

Quick Links

ADC Toxins
Drug-linker Complexes
Customized ADCs
Anti-Ab ADCs

Product List

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Catalog Product name CAS NO Structure Molecular Weight Purity Data sheet Inquiry
ADC-L-Y0173 Amino-PEG5-amine 72236-26-1 Amino-PEG5-amine 280.4 95% Inquiry
ADC-L-Y0174 Amino-PEG6-amine 76927-70-3 Amino-PEG6-amine 324.4 95% Inquiry
ADC-L-Y0175 Amino-PEG7-amine 332941-25-0 Amino-PEG7-amine 368.5 95% Inquiry
ADC-L-Y0176 Amino-PEG8-amine 82209-36-7 Amino-PEG8-amine 412.5 95% Inquiry
ADC-L-Y0177 Amino-PEG9-amine 474082-35-4 Amino-PEG9-amine 456.6 95% Inquiry
ADC-L-Y0178 Amino-PEG10-amine 928292-69-7 Amino-PEG10-amine 500.6 95% Inquiry
ADC-L-Y0179 Amino-PEG11-amine 479200-82-3 Amino-PEG11-amine 544.7 95% Inquiry
ADC-L-Y0180 Amino-PEG23-amine 24991-53-5 Amino-PEG23-amine 1073.3 95% Inquiry
ADC-L-Y0182 Azido-PEG2-amine 166388-57-4 Azido-PEG2-amine 174.2 95% Inquiry
ADC-L-Y0184 Azido-PEG4-amine 951671-92-4 Azido-PEG4-amine 262.3 95% Inquiry
ADC-L-Y0185 Azido-PEG5-amine 516493-93-9 Azido-PEG5-amine 306.4 95% Inquiry
ADC-L-Y0186 Azido-PEG6-amine 957486-82-7 Azido-PEG6-amine 350.4 95% Inquiry
ADC-L-Y0187 Azido-PEG7-amine 1333154-77-0 Azido-PEG7-amine 394.5 95% Inquiry
ADC-L-Y0188 Azido-PEG8-amine 857891-82-8 Azido-PEG8-amine 438.5 95% Inquiry
ADC-L-Y0189 Azido-PEG9-amine 1207714-69-9 Azido-PEG9-amine 482.6 95% Inquiry
ADC-L-Y0190 Azido-PEG10-amine 912849-73-1 Azido-PEG10-amine 526.6 95% Inquiry
ADC-L-Y0191 Azido-PEG11-amine 1800414-71-4 Azido-PEG11-amine 570.7 95% Inquiry
ADC-L-Y0192 Azido-PEG23-amine 749244-38-0 Azido-PEG23-amine 1099.3 95% Inquiry
ADC-L-Y0193 Azido-PEG35-amine 749244-38-0 Azido-PEG35-amine 1628 95% Inquiry
ADC-L-Y0197 Amino-PEG4-t-Boc-hydrazide 1263047-17-1 Amino-PEG4-t-Boc-hydrazide 379.5 95% Inquiry
If you can’t find your product on this list? Please directly send email to info@creative-biolabs.com

For Research Use Only. NOT FOR CLINICAL USE.

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