1. Home
  2. Products
  3. Customized FluoroAb™
  4. FOLR1
  5. Farletuzumab-iFluor 350

Farletuzumab-iFluor 350 (CAT#: ADC-FL-1531)

This product is comprised of an anti-FOLH1 monoclonal antibody (Farletuzumab) labeled with iFluor 350. iFluor 350 is a blue-fluorescent dye and it's excitation/emission is 346/442 nm.

  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • FOLR1
  • Alternative Names
  • FOLH1; folate hydrolase (prostate-specific membrane antigen) 1; FOLH; glutamate carboxypeptidase 2; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase II; NAALAD1; NAALAdase; PSM; PSMA; NAALADase I; membrane glutamate carboxypeptidase; cell
  • Overview
  • This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
  • Overview
  • Humanized Anti-FOLR1 IgG1-kappa antibody, Farletuzumab
  • Generic name
  • Farletuzumab
  • Species Reactivity
  • Human
  • Name
  • iFluor 350
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 346/442
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

Published Data

+ Submit Publications

Submit a review or a question

Scientific Resources

Customer Reviews and FAQs

There are currently no Customer reviews or questions for ADC-FL-1531. Click the button above to contact us or submit your feedback about this product.

Quick Links

Other Products

Same Target
CAT# Product Name Linker Payload
ADC-W-1169 Anti-FOLH1 (Farletuzumab)-MC-Vc-PAB-MMAE ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE
ADC-W-402 Anti-FOLR1 (clone M9346A)-sulfo-SPDB-DM4 ADC sulfo-SPDB DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
ADC-W-602 Anti-FOLR1-S-S-Dox ADC disulfide (“S-S”) linker doxorubicin
ADC-W-1168 Anti-FOLH1 (Farletuzumab)-MC-MMAF ADC MC (maleimidocaproyl) MMAF
ADC-W-562 Anti-FOLR1-DGN462 ADC maleimide containing linkers DGN462

Online Inquiry

Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
Project Description:

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.