shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(CCDC67-shRNA-Seq3)(CAT#: AdV-SI1198WQ)
This product is a CCDC67-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The CCDC67 gene is key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. The expression of CCDC67-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | CCDC67-shRNA-Seq3 |
Related Target/Protein | CCDC67 |
Region | CDS |
TargetSeq | GCAATGACTCAGAATTATGAA |
NCBI RefSeq | NM_181645 |
Alternative Names | DEUP1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Papillary thyroid carcinoma, gastric cancer |