shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(RSBN1-shRNA-Seq2)(CAT#: AdV-SI1076WQ)
This product is a RSBN1-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The RSBN1 gene specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture. The expression of RSBN1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | RSBN1-shRNA-Seq2 |
Related Target/Protein | RSBN1 |
Region | CDS |
TargetSeq | CACTCAGGTCAACAGGACATA |
NCBI RefSeq | NM_018364 |
Alternative Names | KDM9; ROSBIN |
Titer | >1*10^10 GC/mL |
Related Diseases | Breast cancer |