shRNA Lentivirus (self-inactivating), pH1-(HOOK2-shRNA-Seq2)(CAT#: LV-SI2468WQ)
This product is a HOOK2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The HOOK2 gene encodes a member of Hook proteins that are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The expression of HOOK2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | HOOK2-shRNA-Seq2 |
Related Target/Protein | HOOK2 |
Region | CDS |
TargetSeq | GCTATTTGAATGCCGCAACCT |
NCBI RefSeq | NM_013312 |
Alternative Names | HK2 |
Titer | >1*10^10 GC/mL |
Related Diseases | Obesity and type 2 diabetes |