Endotoxin Removal Service
Due to its toxicity, even low levels of endotoxins must be removed before biological samples can be introduced. With rich experience in the field of endotoxin testing, Creative Biolabs deeply understands that the removal of endotoxins from your biological sample is extremely important for downstream applications. We provide a range of endotoxin removal services to effectively reduce the level of endotoxin in your products or other instruments.
Our Services
For each endotoxin removal project, the process of endotoxin removal starts from the basic experimental materials with endotoxin-free. We customize the most suitable protocol for each project and use a simple or combination of several following assays to ensure the highest efficiency of your requirement.
Assay Content
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Extraction Assay
This assay separate endotoxins from target therapeutics based on their relative solubilities in two immiscible liquids.
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Chromatography Assay
This assay consists of several methods including ion exchange chromatography, affinity chromatography, hydrophobic chromatography, gel filtration chromatograph.
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EXLow™ Non-Detergent Assay
EXLow™ non-detergent assay is a detergent-free chromatography method which can lower endotoxin levels below detection.
Usage of Endotoxin Removal Assay
Endotoxin removal assay is necessary for following:
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Recombinant protein
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Peptide
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Biologics
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Monoclonal antibody
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Thrombin
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Plasmid DNA
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Vaccine
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Injection
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Dialysate
Process of Endotoxin Removal
With our endotoxin removal programs, we are confident to make your endotoxin removal project a success.
Fig.1 The workflow of endotoxin removal.
Service Highlights
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Quantitative endotoxin detection assay before and after endotoxin removal
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Reduction of endotoxin levels to less than 0.5 EU/µg
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High accuracy and sensitivity
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Customized removal solutions for individual client needs
Creative Biolabs is the reliable partner for you in effectively reducing the endotoxin level and meeting strict requirements for downstream animal and cell experiments. We offer a full range of assays for different biological samples and instruments. You can purchase the corresponding endotoxin removal products or send samples to seek our one-stop endotoxin removal service. For more detailed information on our endotoxin removal service, please feel free to contact us or directly send us an inquiry.
Reference
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Mason, S.; et al. Current technologies to endotoxin detection and removal for biopharmaceutical purification. Authorea. 2019.
For Research Use Only | Not For Clinical Use
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