Single Mouse Single PK Platform

The Needs for Single Mouse Single PK system

With the increasingly hot market of biological drug research and development, a variety of new molecular types and new targets of biological drugs emerge endlessly, which puts forward higher requirements for the preclinical research of drugs. Especially when the drug target exists only in the human body, how to select the appropriate animal species to complete the preclinical pharmacokinetic study is particularly important. In actual research, transgenic animal models (especially transgenic mice) have been applied more and more, but limited by the limitations of traditional rodent experiment and analysis methods (traditional ELISA), there are usually problems such as large animal consumption, high cost, and large fluctuations in experimental data. In view of the above difficulties and pain points, we have launched a single-mouse- single-PK system to solve the above problems well.

Single Mouse Single PK Platform at Creative Biolabs

At Creative Biolabs, we are proud to offer unparalleled services in the field of pharmacokinetic study with our cutting-edge Single Mouse Single PK Platform. The Single Mouse Single PK Platform revolutionizes the conventional methods by enabling complete PK profiles through serial sampling from a single dosed animal at a specific collection site. This technique not only minimizes animal resource wastage but also enhances sample volume conservation, thereby optimizing the efficiency of drug discovery studies. By utilizing this platform, researchers can obtain comprehensive PK data with reduced variability, leading to more accurate predictions for human dose requirements, providing numerous advantages for drug development endeavors.

Features of Single Mouse Single PK Platform

Compared to the traditional PK system, our Single Mouse Single PK platform has many features as follows:

Innovative Approach	Streamlined Process	Enhanced Data Quality	Ethical Considerations
The Single Mouse Single PK platform offers a novel and efficient method for conducting pharmacokinetic studies, enhancing the accuracy and reliability of data analysis.	By enabling serial sampling from a single-dose mouse, our platform reduces the need for multiple animals, leading to significant cost and resource savings.	Through the implementation of this platform, inter-subject variability in PK data is more effectively controlled, resulting in higher-quality data for improved dose predictions in humans.	The platform aligns with the principles of animal welfare, adhering to the 3 Rs (reduce, refine, replace) to minimize animal resources and ensure humane research practices.

Frequently Asked Questions

Q1: In terms of PK, what are the main challenges facing traditional methods at present?

A1: Traditional methods often face challenges such as animal consumption, high costs, and fluctuating data, hindering the efficiency of drug development.

Our Single Mouse Single PK platform further advances the field of pharmacokinetic research, providing a comprehensive solution for optimizing the drug discovery process and improving research outcomes. If you are interested in our platform, please feel free to contact our technical team.

For Research Use Only | Not For Clinical Use