Close
Close

Dengue Virus S1-S4 Virus-like Particles (DENV S1-S4 VLPs) (CAT#: VLP-016YF)

Datasheet
Dengue Virus S1-S4 Virus-like Particle (DENV S1-S4 VLPs) contains all DENV VLPs from serotypes 1-4. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. DENV VLPs can be used in the development of DENV diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Structural Proteins
  • Capsid protein C, membrane protein M, envelope protein E
  • Expression Systems
  • HEK293 (please specify if other expression system is needed)
  • Purity
  • >95%
  • Form
  • Liquid
  • Alternative Names
  • Dengue Virus S1-S4 Virus-like Particle; DENV S1-4 VLPs; VLPs; Virus-like Particles; DENV Serotype 1-4; Dengue Virus Serotype 1-4
  • Storage
  • Store at -80 °C long term. Avoid repeated freeze/thaw cycles.

Virus Background

  • Virus Family
  • Flaviviridae
  • Virus Species
  • Dengue virus
  • Virus Overview
  • The DENV genome is about 11000 bases of positive-sense, single stranded RNA (ssRNA) that codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5). It also includes short noncoding regions on both the 5' and 3' ends. Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease.
  • Virus Structure
  • Enveloped, positive-sense, single-stranded RNA virus
  • Related Disease
  • Dengue disease

Customer reviews and Q&As    

Customer Review

The perfect immunogen

The mice developed a severe immune response after DENV S1-S4 VLP inoculation.
2022-12-15

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us