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Magic™ Antibody Discovery - Human ALK-7 (21-113) Membrane Protein, Partial, -His tag (CAT#: MP0914F)

Datasheet
This membrane protein is Human ALK-7 (50-254). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ALK-7
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 11.9 kDa. The protein migrates as 15-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 21 - Glu 113 (Accession # Q8NER5-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • ALK-7
  • Full Name
  • activin A receptor type 1C
  • Introduction
  • ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
  • Alternative Names
  • ALK7; ACVRLK7; activin receptor type-1C; ACTR-IC; ALK-7; activin A receptor, type IC; activin receptor type IC; activin receptor-like kinase 7

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