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Magic™ Antibody Discovery - Human Angiopoietin-2 / ANGPT2 (275-496) Membrane Protein, Partial, His- tag (CAT#: MP0926F)

Datasheet
This membrane protein is Human Angiopoietin-2 / ANGPT2 (275-496). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Angiopoietin-2 / ANGPT2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 26.3 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Lys 275 - Phe 496 (Accession # AAI26201.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 20 mM MOPS, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Angiopoietin-2 / ANGPT2
  • Full Name
  • angiopoietin 2
  • Introduction
  • This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
  • Alternative Names
  • ANG2; AGPT2; angiopoietin-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a

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