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Magic™ Antibody Discovery - Human Azurocidin / CAP37 / AZU1 (27-250) Membrane Protein, Partial, -His tag (CAT#: MP0930F)

Datasheet
This membrane protein is Human Azurocidin / CAP37 / AZU1 (1-322). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Azurocidin / CAP37 / AZU1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 25.0 kDa. The protein migrates as 34-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ile 27 - Pro 250 (Accession # AAH69495).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Azurocidin / CAP37 / AZU1
  • Full Name
  • azurocidin 1
  • Introduction
  • Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
  • Alternative Names
  • AZU; HBP; NAZC; hHBP; AZAMP; CAP37; HUMAZUR; azurocidin; cationic antimicrobial protein 37; cationic antimicrobial protein CAP37; heparin-binding protein; neutrophil azurocidin

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