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Magic™ Antibody Discovery - Human B7-H5 / Gi24 / VISTA (33-194) Membrane Protein, Partial, -mIgG2a Fc tag, low endotoxin (CAT#: MP0966F)

Datasheet
This membrane protein is Human B7-H5 / Gi24 / VISTA (10-71). It has been tested in SDS-PAGE, ELISA, BLI, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • B7-H5 / Gi24 / VISTA
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Phe 33 - Ala 194 (Accession # AAH20568.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI, SPR
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • B7-H5 / Gi24 / VISTA
  • Full Name
  • V-set immunoregulatory receptor
  • Introduction
  • Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777)
  • Alternative Names
  • B7H5; GI24; B7-H5; Dies1; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha; V-type immunoglobulin domain-containing suppressor of T-cell activation; Death Domain1alpha; PDCD1 homolog; V-domain Ig suppressor of T cell activation; V-set domain-containing immunoregulatory receptor; platelet receptor GI24; sisp-1; stress-induced secreted protein-1

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