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Magic™ Antibody Discovery - Human CEACAM-6 / CD66c (35-320) Membrane Protein, Partial, -His -Avi tag, [Biotin] (CAT#: MP1292F)

Datasheet
This membrane protein is Human CEACAM-6 / CD66c (35-320). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CEACAM-6 / CD66c
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 34.9 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Lys 35 - Gly 320 (Accession # P40199-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus, followed by an Avi tag.
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CEACAM-6 / CD66c
  • Full Name
  • CEA cell adhesion molecule 6
  • Introduction
  • This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
  • Alternative Names
  • NCA; CEAL; CD66c; carcinoembryonic antigen-related cell adhesion molecule 6; Cluster of Differentiation 66c; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); normal cross-reacting antigen

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