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Magic™ Antibody Discovery - Human FGF basic (143-288) Membrane Protein, Partial (CAT#: MP0112F)

Datasheet
This membrane protein is Human FGF basic (143-288). It has been tested in SDS-PAGE, ELISA, BLI, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FGF basic
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 16.5 kDa. The protein migrates as 17 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Pro 143 - Ser 288 (Accession # P09038-4).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI, SPR
  • Expression Systems
  • E.coli
  • Tag
  • No tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • FGF basic
  • Full Name
  • fibroblast growth factor 2
  • Introduction
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
  • Alternative Names
  • BFGF; FGFB; FGF-2; HBGF-2; fibroblast growth factor 2; basic fibroblast growth factor bFGF; fibroblast growth factor 2 (basic); heparin-binding growth factor 2; prostatropin

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