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Magic™ Antibody Discovery - Human IGFBP-7 (30-282) Membrane Protein, Partial, His- tag (CAT#: MP0881F)

Datasheet
This membrane protein is Human IGFBP-7 (31-992(ITGAV)&22-707(ITGB6)). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IGFBP-7
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 27.0 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Asp 30 - Leu 282 (Accession # NP_001544).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IGFBP-7
  • Full Name
  • insulin like growth factor binding protein 7
  • Introduction
  • This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
  • Alternative Names
  • AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; insulin-like growth factor-binding protein 7; IGF-binding protein 7; IGFBP-rP1; PGI2-stimulating factor; angiomodulin; prostacyclin-stimulating factor; tumor-derived adhesion factor

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